our Health Index for More Subjects, Conditions and
Complex Regional Pain Syndrome (CRPS)
Sympathetic Dystrophy (RSD)
CRPS or RSD are terms
commonly used to describe severe pain and burning in an
upper or lower limb or body part following an injury.
starts with a burning pain and stiffness in an arm or
leg at the site of an injury, but then extends beyond
the original injury. The pain is out of proportion
to the injury.
injury can be the result of something minor such as a
sprain or small laceration or after major trauma,
surgery, crush injuries, fractures, pressure on a nerve,
and radiation therapy.
done and published in the Japanese Journal of Clinical
Medicine* shows this pain to result from injuries to the nervous
With RDS or CRPS,
these nerve injuries many change the way nerve impulses
are sent, causing a "short circuit".
the sheathing of the nerve cells are damaged or degenerate
due to the injury, the signals being transmitted are
scrambled, resulting in your body receiving signals that
are interpreted as numbness, heat, cold, tingling, pain,
This is similar to an
electrical wire that is covered with insulation and the
insulation is beginning to crumble. Without
insulation, the unprotected wire will start
shows up as one or more of the following symptoms:
Burning pain in the
Feeling of cold,
burning or pain in the hands, feet or legs
to touch, even a light touch
The pain is often worse
become healthy again?
It has been known for
some time that increased levels of Thiamine (vitamin B1)
in the blood stream are very effective in building
healthy nerves. Unfortunately, the oral intake
of vitamin B1 does not greatly increase the levels of B1
in the blood stream.
Previously, the way that
blood stream levels of B1 were increased was through
periodic intravenous feeding or through injections every
The reason that
injections have to be used is that thiamine (sometimes
spelled Thiamine) like all the B vitamins, is
water-soluble. Thiamine cannot be stored in the
body and flushes out within 4 to 5 hours.
Oral intake of Thiamine
over 5 mg. results in greatly reduced absorbability, and
is flushed right out of the body (this is why urine
frequently turns yellow when taking larger dosage of B
thy symptoms have been found to be made worse by insufficient
amounts of B12 in the body.
Vitamin B12 supports the
sheathing that protects nerve cells and has shown in
studies to promote the regeneration and growth of nerve
In the past, it has been
difficult to remedy the B12 deficiency. The
reason for this is that, while vitamin B12 is readily
stored by the body, it is not readily absorbed by the
For this reason much
larger amounts have been used in supplementation, but
even large oral dosages have not been an adequate
The most common type of
vitamin B12 used in supplements is called
Cyanocobalamin. Taking Cyanocobalamin can result in
absorption of as little as 1/2 of 1% of the amount
taken, which makes it almost impossible to get enough of
this vitally important vitamin.
In addition, to the very
low absorption, the body must convert the
Cyanocobalamin (which cannot be used by the body) to a
form of vitamin B12 the body can use called
Unfortunately, as the
body gets older, it loses this ability to convert
Cyanocobalamin to Methylcobalamin.
For the above reasons,
as people get older, many physicians recommend regular
monthly injections of vitamins B12 to maintain adequate
body levels or to replenish greatly depleted stores of
this vital nutrient.
A Remedy for
You might have heard of the new type
of vitamin B1 being produced, called Benfotiamine. It is
a fat-soluble version of vitamin B1. What does this
mean? It means this new form of vitamin B1 can be
taken orally in large dosages and it will not flush out
of the body the way ordinary Thiamine (vitamin B1) does.
The result is that by taking
Benfotiamine the blood stream levels of vitamin B1 can
now be greatly increased, nutritionally supporting the
body to build healthy nerves.
Also available is Methylcobalamine
(called Methyl B12). This is the form of vitamin B12
that can be directly utilized by the body and is
available in the quantities nutritionally needed by the
body. Methyl B12 can be taken orally
and is immediately available to the body much like
injectable vitamin B12.
Where can I find these
recommend building health, and nerves are no
are healthy nerves and what is needed to improve their health
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of Clinical Medicine 2001 Sept 59(9): 1655-62
Pathogenesis of Complex Regional Pain Syndrome (CRPS),
Mashimo, T. Department of Anesthesiology and Acute
Critical Medicine, Osaka University Medical School
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